The major psychoactive component in marijuana is delta- 9- tetrahydrocannabinol, or thc. cbd oil for pediatric epilepsy foundation. after entering the bloodstream through blood- gas exchanges associated with smoking, thc combines with receptor sites in the human brain to cause drowsiness, increased appetite, giddiness, hallucinations, and other psychoactive effects. cannabis ( ie, marijuana) is a plant that contains a complex mixture of chemicals called cannabinoids. examples of cannabinoids include tetrahydrocannabinol ( thc) and cannabidiol ( cbd). whereas thc is primarily responsible for the psychoactive effects ( euphoria) of cannabis, cbd may decrease pain but causes far fewer psychoactive effects than thc. the psychoactive effects of cannabis, known as a " high", are subjective and vary among persons and the method of use. kratom extract preparation online. when thc enters the blood stream and reaches the brain, it binds to cannabinoid receptors. the endogenous ligand of these receptors is anandamide, the effects of which thc emulates. delta9- tetrahydrocannabinol, or thc for short, is the active substance found in marijuana.
it is responsible for its psychoactive effects. thc binds to cannabinoid receptors found in certain areas. thc, marijuana’ s principal psychoactive component, makes a person feel high by binding to cb1, the most abundant protein receptor in the brain and central nervous system. thc fits snugly into a special pocket – an “ orthosteric” binding site – on the cb1 receptor. the psychoactive effects of cannabis depend on thc’ s ability to activate the cb1 receptor. the presence of cbd changes thc’ s ability to activate cb1 receptors and laboratory studies in both. cannabis contains the chemical psychoactive effects of cannabis compound thc ( delta- 9 tetrahydrocannabinol), which is believed to be responsible for most of the characteristic psychoactive effects of cannabis that leads to the " high" that is experienced when cannabis is consumed. however, not all components of cannabis are psychoactive.
the main psychoactive ingredient, thc,. “ the health effects of cannabis and cannabinoids: the current state of evidence and recommendations for research. webmd does not provide medical. these side effects are part of the compound’ s psychoactive properties. neither compound is fatal. however, high thc use may be connected to long- term negative psychiatric effects. the effects of the 120- plus cannabinoids present in cannabis are mostly unknown, but the most potent psychoactive agent identified to date is thc. when a person smokes cannabis, thc is quickly.